Sammanställning av godkända forskningsprojekt

Ansvarig forskare Lärosäte Projektnamn Publikationer
Helena Carén GU Improved diagnostics of pediatric CNS tumors based on DNA methylation classification
Monica Nistér/
Joakim Lundeberg		 KTH/KI Analysis of spatial gene expression in childhood brain tumors Spatially resolved clonal copy number alterations in benign and malignant tissue
John Inge Johnsen/
Ninib Baryawno		 KI/K Single cell RNA-seq of childhood brain tumorus Genomic tumor evolution dictates human medulloblastoma progression
Fredrik Swartling UU Developing xenografts and cell lines from CNS tumors in children for molecular studies and novel treatment models
Emma Tham/
Magnus Nordenskjöld		 KI/K Analys av cell-fritt tumör-DNA i blod och cerebrospinalvätska
Anna Pasetto KI Nya immunterapier för barnhjärncancer (hjärnstam/ ponsgliom) Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma
Anna Dahlin UmU Genotyp-fenotyp studier i barnhjärntumörer
Lisa Westerberg KI Studier av pediatriskt lymfom
Klas Blomgren KI/K Studier av tumörceller och immunceller vid hjärntumörer hos barn
Peter Lundberg RÖ/LiU Förbättrad diagnostik av tumörer i centrala nervsystemet hos barn och ungdomar genom applicering digital patologi Pediatric brain tumor classification using digital histopathology and deep learning: evaluation of SOTA methods on a multi-center Swedish cohort
Petter Brodin/Per Kogner KI ISAC: immune monitoring of pediatric cancer patients Systems-level immunomonitoring in children with solid tumors to enable precision medicine
Gustaf Ljungman UU/LiU Pharmacogenomics in pediatric oncology patients with focus on chemotherpay-induced toxicity including myelosuppression
Martin Dalin GU Personalized analysis of circulating tumor DNA: A guide for treatment decisions in childhood cancer
Helena Carén GU Integrated analyses of paediatric brain tumours focusing on epigenetic aberrations
Lena-Maria Carlsson K LOGGIC Core – En internationell molekylär databas för låggradiga gliom hos barn
Svetlana Lagercrantz K Molekylär karakterisering och kliniska aspekter på familjära cancersyndrom orsakade av TP53 mutationer i den svenska befolkningen
Anna Dahlin UmU Genotype-Phenotype Investigations in Childhood Brain Tumors – Phase II
Felix Haglund K/KI Proteogenomic and functional characterization of sarcomas in a prospective clinical setting
Susanne Schlisio KI Utforska Neuroblastom – cellstadiedynamik och plasticitet vid tumörbildning och terapiresistens
Fredrik Bäcklund RU/K Genetiska förändringar i lymfom hos barn
Sten Linnarsson KI Cell identity in adult and pediatric brain tumors
Erik Sundström KI Pediatric ependymoma – defining cell state transitions as basis for future treatments
Emma Tham KI The use of cerebrospinal fluid for diagnosis, prognosis and monitoring of treatment response in patients with childhood brain tumors