Sammanställning av godkända forskningsprojekt

Ansvarig forskare

Lärosäte

Projektnamn

Publikationer

Helena Carén

GU

Improved diagnostics of pediatric CNS tumors based on DNA methylation classification

 

 

Monica Nistér/
 Joakim Lundeberg

KTH/KI

Analysis of spatial gene expression in childhood brain tumors

 

Spatially resolved clonal copy number alterations in benign and malignant tissue

John Inge Johnsen/

Ninib Baryawno

KI/K

Single cell RNA-seq of childhood brain tumorus

Genomic tumor evolution dictates human medulloblastoma progression

 

Fredrik Swartling

UU

Developing xenografts and cell lines from CNS tumors in children for molecular studies and novel treatment models

 

 

Emma Tham/

Magnus Nordenskjöld

KI/K

Analys av cell-fritt tumör-DNA i blod och cerebrospinalvätska

 

 

Anna Pasetto

KI

Nya immunterapier för barnhjärncancer (hjärnstam/ ponsgliom)

Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma

 

Anna Dahlin

UmU

Genotyp-fenotyp studier i barnhjärntumörer

 

 

Lisa Westerberg

KI

Studier av pediatriskt lymfom

 

 

Klas Blomgren

KI/K

Studier av tumörceller och immunceller vid hjärntumörer hos barn

 

 

Peter Lundberg

RÖ/LiU

Förbättrad diagnostik av tumörer i centrala nervsystemet hos barn och ungdomar genom applicering digital patologi

 

Pediatric brain tumor classification using digital histopathology and deep learning: evaluation of SOTA methods on a multi-center Swedish cohort

Petter Brodin/Per Kogner

KI

ISAC: immune monitoring of pediatric cancer patients

Systems-level immunomonitoring in children with solid tumors to enable precision medicine

 

Gustaf Ljungman

UU/LiU

Pharmacogenomics in pediatric oncology patients with focus on chemotherpay-induced toxicity including myelosuppression

 

 

Martin Dalin

GU

Personalized analysis of circulating tumor DNA: A guide for treatment decisions in childhood cancer

 

 

Helena Carén

GU

Integrated analyses of paediatric brain tumours focusing on epigenetic aberrations

 

 

Lena-Maria Carlsson

K

LOGGIC Core – En internationell molekylär databas för låggradiga gliom hos barn

 

 

Svetlana Lagercrantz

K

Molekylär karakterisering och kliniska aspekter på familjära cancersyndrom orsakade av TP53 mutationer i den svenska befolkningen

 

 

Anna Dahlin

UmU

Genotype-Phenotype Investigations in Childhood Brain Tumors – Phase II

 

 

Felix Haglund

K/KI

Proteogenomic and functional characterization of sarcomas in a prospective clinical setting

 

 

Susanne Schlisio

KI

Utforska Neuroblastom – cellstadiedynamik och plasticitet vid tumörbildning och terapiresistens

 

 

Fredrik Bäcklund

RU/K

Genetiska förändringar i lymfom hos barn

 

 

Sten Linnarsson

KI

Cell identity in adult and pediatric brain tumors

 

 

Erik Sundström

KI

Pediatric ependymoma – defining cell state transitions as basis for future treatments

 

 

Emma Tham

KI

The use of cerebrospinal fluid for diagnosis, prognosis and monitoring of treatment response in patients with childhood brain tumors