Sammanställning av godkända forskningsprojekt
Nedan presenteras forskningsprojekt som har godkänts för tillgång till prover och/eller data från Barntumörbanken. Sammanställningen omfattar både pågående och avslutade projekt.
| Sökande | Lärosäte/huvudman | Projekttitel |
|---|---|---|
| Helena Carén | GU | Improved diagnostics of paediatric CNS tumours based on DNA methylation classification |
| Monica Nistér and Joakim Lundeberg | KI/KTH | Analysis of spatial gene expression in childhood brain tumours |
| John Inge Johnsen and Ninib Baryawno | KI/K | Single-cell RNA sequencing of childhood brain tumours |
| Fredrik Johansson Swartling | UU | Developing xenografts and cell lines from CNS tumours in children for molecular studies and novel treatment models |
| Emma Tham and Magnus Nordenskjöld | KI/K | Analysis of cell-free tumour DNA in blood and cerebrospinal fluid |
| Anna Pasetto | KI | Novel immunotherapies for childhood brain cancer (brainstem/pons glioma) |
| Lisa Westerberg | KI | Paediatric lymphoma studies using single-cell RNA sequencing |
| Klas Blomgren | KI/K | Studies of tumour cells and immune cells in paediatric brain tumours |
| Peter Lundberg and Neda Haj-Hosseini | RÖ/LiU | Improved diagnosis of central nervous system tumours in children and adolescents through the application of digital pathology (AI) |
| Petter Brodin and Per Kogner | K/KI | ISAC: Immune monitoring of paediatric cancer patients |
| Gustaf Ljungman and Henrik Green | UU/LiU | Pharmacogenomics in paediatric oncology patients, with a focus on chemotherapy-induced toxicity, including myelosuppression |
| Martin Dalin | GU | Personalised analysis of circulating tumour DNA: A guide for treatment decisions in childhood cancer |
| Helena Carén | GU | Integrated analyses of paediatric brain tumours, focusing on epigenetic aberrations |
| Lena-Maria Carlsson | K | LOGGIC Core BioClinical Data Bank – LOGGIC: Low-grade Glioma in Children |
| Svetlana Lagercrantz | K | Genomic and clinical characterisation of TP53-related paediatric tumours |
| Anna Dahlin | UmU | Genotype–phenotype investigations in childhood brain tumours – Phase II |
| Susanne Schlisio | KI | Exploring neuroblastoma – cell-state dynamics and plasticity in tumour development and therapy resistance |
| Felix Haglund | K/KI | Proteogenomic and functional characterisation of sarcomas in a prospective clinical setting |
| Fredrik Bäcklund | RU/K | Genetic landscape of lymphomas in children and adolescents |
| Sten Linnarsson | KI | Cell identity in adult and paediatric brain tumours |
| Erik Sundström | KI | Paediatric ependymoma – defining cell-state transitions as a basis for future treatments |
| Emma Tham | K (UU, RU, GU, VGR) | The use of cerebrospinal fluid for diagnosis, prognosis and monitoring of treatment response in patients with childhood brain tumours |
| Margareta Wilhelm | KI | Genetic and epigenetic studies of medulloblastoma |
| Karolin Hansén Nord | LU | Deciphering one of the most complex cancer genomes to understand the dual role of TP53 |
| Sandra Wessman and Nikolas Herold | K/KI | TOP2A as a biomarker of response to anthracycline treatment |
| Ida Maria Westin | UmU | Genetic and cellular mechanisms underlying the development of paediatric brain tumours |
| Kenny Rodriguez-Wallberg | K/KI | Late effects following chemotherapy-induced organ damage – identification of timing, interactions and genetic biomarkers for predictive modelling in precision cancer treatment |