Immunogenomic profiling reveals targets for gene therapy in pediatric brain tumors
Rovesti G, Fernandez Woodbridge A, Yao H, Pancaldi A, Chiavelli C, Gatto F, Sandvick U, Sällberg M, Fuxe J, Dominici M, Grönlund H, Nilsson OB, Nascimento Silva D, Pasetto A.
Neuro-Oncology Advances. 2026;8(1). DOI: 10.1093/noajnl/vdag193. PMID: 42592420
[Preprint] Spatial mapping of pediatric brain tumors across diagnoses and relapses
Escudero Morlanes J, Lehto TP, Larsson L, Alonso Galicia L, Mollbrink A, Shamikh A, Basmaci E, Prochazka G, Díaz de Ståhl T, Sandgren J, Taylan F, Tesi B, Nordgren A, Erickson A, Lamb AD, Blomgren K, Nistér M, Lundeberg J, Mirzazadeh R, Kvastad L.
bioRxiv. 2026 Aug 26. Preprint – not peer reviewed. doi: 10.64898/2026.08.25.746606
[Preprint] A Multicenter Swedish Histopathology Image Dataset of Pediatric Central Nervous System Tumors
Nyman P, Tampu IE, Shamikh A, Prochazka G, Blystad I, Basmaci E, Díaz de Ståhl T, Augustsson P, Zielinska-Chomej K, Cao D, von Salomé J, Ardalan A, Somarajan PR, Ljungman G, Lundberg P, Sandgren J, Haj-Hosseini N.
medRxiv. 2026. Preprint – not peer reviewed. doi: https://doi.org/10.64898/2026.06.15.26355523
Novel activating SNRNP70-ALK fusion in congenital infant-type hemispheric glioma displays clinical response to lorlatinib: a case-report
Cecilia Arthur, Kleopatra Georgantzi, Teresita Díaz de Ståhl, Jikui Guan, Blaz Oder, Cecilia Jylhä, Christopher Illies, Johanna Sandgren, Jan Svoboda, Jesper Eisfeldt, Gisela Barbany, Richard Rosenquist, Ulrika Sandvik, Daniel Hägerstrand, Bengt Hallberg, Ruth Palmer, Emma Tham
NPJ Precis Oncol. 2026 Feb 26;10(1):113. doi: 10.1038/s41698-026-01336-x.
Pediatric brain tumor classification using digital pathology and deep learning: Evaluation of SOTA methods on a multi-center Swedish cohort
Iulian Emil Tampu, Per Nyman, Christoforos Spyretos, Ida Blystad, Alia Shamikh, Gabriela Prochazka, Teresita Díaz de Ståhl, Johanna Sandgren, Peter Lundberg, Neda Haj-Hosseini.
Brain Pathol. 2026 Jan;36(1):e70029. doi: 10.1111/bpa.70029.
Systems-level immunomonitoring in children with solid tumors to enable precision medicine
Qi Chen, Binbin Zhao, Ziyang Tan, Gustav Hedberg, Jun Wang, Laura Gonzalez, Constantin Habimana Mugabo, Anette Johnsson, Erika Negrini, Laura Piñero Páez, Lucie Rodriguez, Anna James, Yang Chen, Jaromír Mikeš, Anna Karin Bernhardsson, Stefan Markus Reitzner, Ferdinand von Walden, Olivia O’Neill, Hugo Barcenilla, Chunlin Wang, Mark M. Davis, Lena-Maria Carlson, Niklas Pal, Klas Blomgren, Dirk Repsilber, Nikolas Herold, Tadepally Lakshmikanth, Per Kogner, Linda Ljungblad, Petter Brodin.
Cell, Volume 188, Issue 5, 2025, Pages 1425-1440. https://doi.org/10.1016/j.cell.2024.12.014.
Genomic tumor evolution dictates human medulloblastoma progression
Ruchiy Y, Tsea I, Preka E, Verhoeven BM, Olsen TK, Mei S, Sinha I, Blomgren K, Carlson LM, Dyberg C, Johnsen JI, Baryawno N. Neurooncol Adv. 2024 Oct 5;6(1):vdae172. doi: 10.1093/noajnl/vdae172. PMID: 39659836; PMCID: PMC11629688.
The potential of liquid biopsy for detection of the KIAA1549-BRAF fusion in circulating tumor DNA from children with pilocytic astrocytoma
Krynina O, de Ståhl TD, Jylhä C, Arthur C, Giraud G, Nyman P, Fritzberg A, Sandgren J, Tham E, Sandvik U. Neurooncol Adv. 2024 Jan 24;6(1):vdae008 | https://doi.org/10.1016/j.lanepe.2024.100881
Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors – a nationwide, prospective Swedish study
Bianca Tesi, Kristina Lagerstedt Robinson, Frida Abel,Teresita Díaz de Ståhl, Sara Orrsjö, Anna Poluha,Maria Hellberg, Sandra Wessman, Sofie Samuelsson, Tony Frisk, Hartmut Vogt, Karin Henning, Magnus Sabel, Torben Ek, Niklas Pal, Per Nyman, Geraldine Giraud et al. The Lancet Regional Health Europe, March 2024 | https://doi.org/10.1016/j.lanepe.2024.100881
Implementing data on targeted therapy from the INFORM registry platform for children with relapsed cancer in Sweden
Wallin S, Øra I, Prochazka G, Sandgren J, Björklund C, Ljungman G, Vogt H, Ek T, Van Tilburg C, Nilsson A. Front. Oncol. Sec. Pediatric Oncology Volume 14 – 2024 | doi: 10.3389/fonc.2024.1340099
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer
Wadensten E, Wessman S, Abel F, Diaz De Ståhl T, Tesi B, Orsmark Pietras C, Arvidsson L, Taylan F, Fransson S, Vogt H, Poluha A, Pradhananga S, Hellberg M, Lagerstedt-Robinson K, Raj Somarajan P, Samuelsson S, Orrsjö S, Maqbool K, Henning K, Strid T, Ek T, Fagman H, Olsson Bontell T, Martinsson T, Puls F, Kogner P, Wirta V, Pronk CJ, Wille J, Rosenquist R, Nistér M, Mertens F, Sabel M, Norén-Nyström U, Grillner P, Nordgren A, Ljungman G, Sandgren J, Gisselsson D JCO Precis Oncol. 2023 Jun;7:e2300039. doi: 10.1200/PO.23.00039. PMID: 37384868; PMCID: PMC10581599.
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden
Díaz de Ståhl T, Shamikh A, Mayrhofer M, Juhos S, Basmaci E, Prochazka G, Garcia M, Somarajan PR, Zielinska-Chomej K, Illies C, Øra I, Siesjö P, Sandström PE, Stenman J, Sabel M, Gustavsson B, Kogner P, Pfeifer S, Ljungman G, Sandgren J, Nistér M. J Transl Med. 2023 May 23;21(1):342. doi: 10.1186/s12967-023-04178-4. PMID: 37221626; PMCID: PMC10204274.
Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma
Arthur C, Jylhä C, de Ståhl TD, Shamikh A, Sandgren J, Rosenquist R, Nordenskjöld M, Harila A, Barbany G, Sandvik U, Tham E. Cancers (Basel). 2023 Mar 25;15(7):1972. doi: 10.3390/cancers15071972. PMID: 37046633; PMCID: PMC10092983.
Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples
Mirzazadeh R, Andrusivova Z, Larsson L, Newton PT, Galicia LA, Abalo XM, Avijgan M, Kvastad L, Denadai-Souza A, Stakenborg N, Firsova AB, Shamikh A, Jurek A, Schultz N, Nistér M, Samakovlis C, Boeckxstaens G, Lundeberg J.
Nat Commun. 2023 Jan 31;14(1):509.
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants
Garcia M, Juhos S, Larsson M, Olason PI, Martin M, Eisfeldt J, DiLorenzo S, Sandgren J, Díaz De Ståhl T, Ewels P, Wirta V, Nistér M, Käller M, Nystedt B. F1000Res. 2020 Jan 29;9:63.
Spatially resolved clonal copy number alterations in benign and malignant tissue
Erickson A, He M, Berglund E, Marklund M, Mirzazadeh R, Schultz N, Kvastad L, Andersson A, Bergenstråhle L, Bergenstråhle J, Larsson L, Alonso Galicia L, Shamikh A, Basmaci E, Díaz De Ståhl T, Rajakumar T, Doultsinos D, Thrane K, Ji AL, Khavari PA, Tarish F, Tanoglidi A, Maaskola J, Colling R, Mirtti T, Hamdy FC, Woodcock DJ, Helleday T, Mills IG, Lamb AD, Lundeberg J. Nature. 2022 Aug;608(7922):360-367. doi: 10.1038/s41586-022-05023-2. Epub 2022 Aug 10. PMID: 35948708; PMCID: PMC9365699.
Amplification of ERBB2 (HER2) in embryonal rhabdomyosarcoma: A potential treatment target in rare cases?
Mitra S, Sydow S, Magnusson L, Piccinelli P, Törnudd L, Øra I, Ljungman G, Sandgren J, Gisselsson D, Mertens F. Genes Chromosomes Cancer. 2022 Jan;61(1):5-9. doi: 10.1002/gcc.22996.
Pediatric Soft Tissue Sarcoma in Limb-Girdle Muscular Dystrophy: Molecular Findings and Clinical Implications
Maya-González C, Díaz De Ståhl T, Wessman S, Taylan F, Tesi B, Lagerstedt-Robinson K, Tettamanti G, Dukic M, Poluha A, Ljungman G, Nordgren A.
Am J Case Rep. 2024 Dec 29;25:e945715. doi: 10.12659/AJCR.945715. PMID: 39733240.
Occurrence of cancer in Marfan syndrome: Report of two patients with neuroblastoma and review of the literature
Maya-González C, Delgado-Vega AM, Taylan F, Lagerstedt Robinson K, Hansson L, Pal N, Fagman H, Puls F, Wessman S, Stenman J, Georgantzi K, Fransson S, Díaz De Ståhl T, Ek T, Palmer R, Tesi B, Kogner P, Martinsson T, Nordgren A.
Am J Med Genet A. 2024 Dec;194(12):e63812. doi: 10.1002/ajmg.a.63812. PMID: 38990105.